Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae
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چکیده
منابع مشابه
Functional Dissection of the Nascent Polypeptide-Associated Complex in Saccharomyces cerevisiae.
Both the yeast nascent polypeptide-associated complex (NAC) and the Hsp40/70-based chaperone system RAC-Ssb are systems tethered to the ribosome to assist cotranslational processes such as folding of nascent polypeptides. While loss of NAC does not cause phenotypic changes in yeast, the simultaneous deletion of genes coding for NAC and the chaperone Ssb (nacΔssbΔ) leads to strongly aggravated d...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0143457